Biologic treatment for degenerative disc disease includes both protein-based and cell-based therapies. The goal of these therapies is to innervate the damaged intervertebral disc to enhance regeneration, delay degeneration or impede inflammation.
The Via Disc nucleus pulposus tissue allograph is an outpatient surgical procedure, where the biologic is delivered directly to the degenerated discs through an intradiscal injection. The disc tissue particulate component and cell component of VIA Disc are mixed together with saline for injection into your intervertebral disc.
VIA Disc is intended for use as an allograft to supplement degenerated intervertebral discs. An allograft is tissue recovered from a human cadaveric donor that is transferred to a human recipient. Allograft transplantation has long been accepted as an effective option to treat a wide variety of orthopedic and spine-related issues.
VIA Disc consists of two key allograft components, the intervertebral disc tissue particulate, and spine-derived cells. Both will be injected with saline into your intervertebral disc during a non-surgical spinal procedure.
The VIA Disc procedure is performed under strict sterile conditions. The VIA Disc procedure can be performed under local anesthesia or moderate sedation may be recommended by your physician. An injection into the pain-generating intervertebral disc can be painful. During the procedure, your physician will use fluoroscopy (a computer tomography scan that continues to take images during the procedure so that the physician can see where the needle is going). Your physician will insert a needle through the skin and muscle into the center of the spinal disc. VIA Disc will be slowly injected into the center of the spinal disc. The injection procedure generally takes about 20 to 30 minutes.
Age-related wear and tear of the intervertebral discs can cause loss of hydration and degeneration. One of the most common causes of chronic low back pain is the degeneration of the disc. Not all degenerated discs cause pain, but painful disc degeneration most commonly occurs in the low back (or lumbar spine). The low lumbar spine carries a significant weight-bearing function and supports substantial rotational and translational movement, making the area susceptible to injury.
Discogenic low back pain can be determined through a combination of symptoms, physical examination and imaging. Pain typically manifests itself as medial back pain with or without radicular leg pain. Further identification focuses on determining the directional forces that worsen symptoms.With discogenic low back pain, shear forces push down and load the spine, applying pressure to the disc. Therefore, pain is exacerbated most when leaning forward as this weight-bearing position puts the most pressure on the painful disc.
If left untreated, continued degeneration of intervertebral discs can manifest in increased pain and spinal instability. Degenerated discs can increase your risk of developing other spinal conditions, including osteoarthritis, scoliosis, spinal stenosis, spondylolisthesis, and spondylolysis. It may also affect your balance, functionality and ability to perform day-to-day activities